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The Dentistry Service of the University of Pennsylvania Veterinary Hospital is currently recruiting cats with oral stomatitis for a pilot study to evaluate the effectiveness of a new drug when injected into oral lesions. Knowledge gained from this study may provide an advancement in the treatment of feline stomatitis, and possibly similar conditions seen in humans. We are seeking ten cats with bilateral caudal stomatitis to be enrolled as a pilot to evaluate the potential for future studies.

Feline stomatitis is a poorly understood inflammatory disease of the oral mucosal linings which causes pain and suffering in domestic cats. Symptoms of oral pain include decreased appetite, vocalizing when eating, yawning or opening the mouth, and drooling. Severe chronic inflammation is seen in the gums and adjacent soft tissues around the teeth and in the back of the mouth, making it difficult to chew and swallow. Full-mouth extraction is currently the treatment of choice, which does provide significant benefit in approximately 80% of affected cats. However, approximately 20% of cats that underwent surgical extractions have continued inflammation and pain.

Criteria Include:

must be deemed to be otherwise healthy based on physical
examination and blood work.

must be previously diagnosed with bilateral caudal mucositis which has been unresponsive to other treatments, including full-mouth (or nearly full-mouth)

Enrollment will finish May 15, 2012 or when 10 cats have been enrolled.

you are interested in enrolling a patient for this study, or would like more information, please contact the Veterinary Clinical Investigations Center at 215-573-0302 or



In Cats

Hi, I have 2 female cats ages 2 and 4, and one male cat who is about to turn 12.  My concern is with the girls.  My boyfriend and I moved in together almost a year ago.  I already owned Simon and Sophia and he owned Haylee.  Simon is not the issue because he is the most layed back cat you will ever meet.  Haylee was very neglected as a kitten and saved by my boyfriend.  Sophia is feisty and likes things to be her way.  We took our time and did everything we could to introduce them gradually.  We used Feliway and it seemed to have an adverse effect on Sophia.  We kept each in a different room and used blankets and toys to exchange each other's scent.  We had them play on either side of the door and rewarded with treats.  We let each cat have a chance to roam the remainder of the house on their own.  We opened the door just a little to let them start peeking at each other.  Finally, we let them have free rein of the house.  However, we are not so pleased with the relationship they currently have, stalking each other, hissing and growling, sneaking up on each other.  Things improved but are not great.  Haylee is also trying to adjust to having me.  Her abuser was a female so she is apprehensive but we are getting their.  I just feel bad that I can't show her the same affection as I do Simon and Sophia...maybe that plays a part in all of this?

So we are about to move again.  I was wondering if I should repeat the process of introducing them.  If so, should I do anything differently?  How long should this take?  The benefit to moving is everyone will have more space now! ANY advice would be greatly appreciated! 

Hilary, Simon, Sophia, and Haylee

This has been going on one month.  My tenant died and her cat is hiding in a very inaccesable spot.  She found a hole in a closet and now hides in the frame work of the upstairs apt.  Trapping her with food, in a humain trap has been a complete failure. She has been existing on only the small pieces of food I leave to tempt her to the food in the trap release.  She never goes near it.  I have three traps.  I do leave out water. She uses her litter box in the middle of the night so I do know she is alive.  Please help.  I have pulled out all the walls that would give me access to her but no luck.  If she dies she is going to die where I can't get to her.  What else do I do????  I am a cat lover with five cats of my own.  This has me in tears.  

I have recently adopted a Russian Blue rescue cat, he was left alone for a very long period without food, apart from being very thin, he is a wonderful cat, full of love and fun and I am setting about feeding him up and giving him a lot of fuss!  Only problem I have come across is he doesn't seem to sleep at night, instead he will meow loudly through the night whether I let him in the bedroom or not.  Is there any advice you can offer as to why he is doing this? I appreciate this breed is very intelligent, I have shown him his litter tray and toys and food which he has remembered all and uses frequetly but he doesn't seem to be interested in his bed and I am not getting a wink of sleep.  He clearly wants to be around me a lot and is very affectionate, other than craving attention, any ideas why he meow's so loudly and contstantly at night? Thanks.

I have cat that I had to bottle feed from a kitten cause his mother was run over.  He was a few weeks old, and my mothers cat was hit by a car, leaving 4 kittens behind.  They were not going to worry about the one i took cause he was blind.  We took him home, bottle fed him, and about 3 months later, his eyes cleared up and he is able to see!!!  We have had problems with him since he was a kitten with not always using the litter box.  As he has gotten older, he is better, but he still refuses to use it all the time.  He will pick different places all over the house, and as we get him to stop in one place, he just finds another "favorite place" to go.   We have had him for 2 years.  He is nutered and declawed, but my husband is so beyond done with finding poo all over.  PLEASE help me so we can keep my little kitty! 

   Both cats saw our Mobile vet friday for annual exam and shots.  Mickey a short hair grey male tabby cat of 3 yr walked into the cat carrier with no problem. As soon as the door closed he went nuts.  Vet sprayed him with some thing that was suppose to help him calm down.  It did not. 

   Back into the house we let him go in the bedroom where his safe spot is.  Since then when he spots his house mate of three yrs he starts hissing, growl, hair goes up and he swats at Sasha ( black/tan short hair female) and then runs.  She at frist tryed to touch noises but now gos into attack mode.  We have a full ongoing war.  and they are fully clawed.

   We have now set up space just for Mickey in the bedroom/bath and keeping the door close ... feeding etc by himself.... any suggests on how to go forward would be very welcome ... this is very stress full on everyone in the house...

    He has all ways ran and hid when someone came to the door.  But with everyone in the house specialy  his with his playmate Sasha he has been loving, playful no other problems ....  

Hi - I'm new and hoping someone can help me with this problem.  I have three cats - 2 are siblings, a male and a female, about 5 yrs. old, the other is a Siamese, about 12.  All three are active and in good health.  One of them, probably one of the younger cats, has been defecating and urinating just outside the litter boxes for about a month, usually in the same spot.  We have three litter boxes in the basement and they are easily reached.  I eliminated the Siamese being the culprit by isolating him for a couple of days.  This behavior has never happened before, and, as far as I know, nothing has changed in our environment or situation.




In Cats

i have a question,

is it normal for a cat to shy away from opening doors even if they are silent, or run from their owner? i've had my cat 8 yearss now, and has never done this before. could it be rusult of her age(8yrs)? she also runs from end to end in my yard not chasing anytihng, do they do this as intinct or what? i just want to make sure everything is okay with her and that her behavior be either normal or not. thnx.



In Cats

My cat (20 years old) has been having problems with her right hind leg for a while (arthritis).  Suddenly, a couple of days ago, she couldn't stand up or walk.  Both of her hind legs were too weak to support her.  My usual vet says arthitis has encased her spinal cord.  I want to try acupuncture before I even consider the FINAL SOLUTION.  I cry when she tries to tell me what she wants.  I always carry her to the litter box first, then try to give her water, then try food.  Her appetite is good - she is very alert- but I don't know how long we can go on with a 24/7 watch on her.

I guess, I don't know what I am asking except for others who have gone thru this.  I cannot bring myself to to make that final decision.




In Cats

I have a cat thats 18 years old. She has hypothyroidism and is on medication for that. I have begun to wonder if she is becoming senile. She always used her litter box and has always been a good cat. In about the past year she has begun to mainly sleep. When she has the urge to go to the bathroom..she will 'go' wherever she happens to be. She has literally stood up from the spot where she was sleeping.near her food dish,squatted and urinated and/or pooped. Not only that..she has been known to do this in other strange places. She has gotten on the dinner table and urinated. She has came running into my room and jumped staright up onto my bed and squatted and urinated. She has urinated in the dogs food dish. pooped in the bathtub, just anytime the urge hits her..she goes.. any place,anytime,anywhere. This is not the beloved cat we once knew. We are at our wits end on what to do. We don't have the money for alot of tests. When we took her to the vet he said to be 18 years old she looked very healthy, though she only weighs about 5 pounds..she used to be very fat. We have tried taking her to her box in the bathroom after meals and in between. She will use the she knows what its for and where its at. She occassionally goes to her box on her own. is there anyone out there dealing with a situation like this? All answers appreciated.

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